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rs6265
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BDNF
Val66Met
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Key neurotrophin variant that controls activity-dependent BDNF release, affec...
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Neurology & Cognition
|
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Strong
|
|
rs1042713
|
ADRB2
Arg16Gly
|
Beta-2 adrenergic receptor variant affecting receptor downregulation, exercis...
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Fitness & Body
|
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Strong
|
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rs4253778
|
PPARA
intron 7 G/C
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Regulates fatty acid oxidation and muscle fiber composition, influencing endu...
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Fitness & Body
|
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Moderate
|
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rs356182
|
SNCA
|
Parkinson's disease GWAS risk variant affecting alpha-synuclein expression an...
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Neurology & Cognition
|
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Strong
|
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rs9939609
|
FTO
Intron 1 T>A
|
The most strongly replicated obesity-associated variant, affecting body weigh...
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Energy & Weight
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Established
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rs17602729
|
AMPD1
C34T (Q12X)
|
Enzyme critical for energy production during high-intensity exercise; deficie...
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Fitness & Body
|
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Strong
|
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rs3736228
|
LRP5
A1330V
|
Wnt signaling co-receptor variant affecting bone mineral density and fracture...
|
Fitness & Body
|
|
Strong
|
|
rs1801253
|
ADRB1
Arg389Gly
|
Beta-1 adrenergic receptor variant where Arg389 produces higher basal activit...
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Fitness & Body
|
|
Strong
|
|
rs2016520
|
PPARD
+294T>C
|
Regulatory variant that increases PPARD transcription, enhancing fat oxidatio...
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Fitness & Body
|
|
Moderate
|
|
rs1053049
|
PPARD
3'UTR variant
|
3'UTR variant in PPARD that acts as the third tag in the elite athlete haplot...
|
Fitness & Body
|
|
Moderate
|
|
rs2267668
|
PPARD
Intron variant (5' region)
|
Intronic PPARD variant that impairs aerobic fitness gains and body compositio...
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Fitness & Body
|
|
Moderate
|
|
rs1800764
|
ACE
Promoter T>C
|
Upstream promoter-region ACE variant on a separate LD block from the I/D poly...
|
Fitness & Body
|
|
Moderate
|
|
rs6902123
|
PPARD
|
Intronic PPARD variant that independently impairs hepatic fat mobilization du...
|
Fitness & Body
|
|
Moderate
|
|
rs891512
|
NOS3
|
Intronic NOS3 variant that alters splicing factor binding and is associated w...
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Vitamins & Micronutrients
|
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Moderate
|