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rs5443
|
GNB3
C825T
|
Synonymous exon-10 variant that triggers alternative splicing of the G-protei...
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Hormones & Sleep
|
|
Strong
|
|
rs1801253
|
ADRB1
Arg389Gly
|
Beta-1 adrenergic receptor variant where Arg389 produces higher basal activit...
|
Fitness & Body
|
|
Strong
|
|
rs2681472
|
ATP2B1
|
Intronic regulatory variant near the PMCA1 calcium pump gene, one of the most...
|
Heart & Inflammation
|
|
Strong
|
|
rs1799998
|
CYP11B2
-344C>T
|
Promoter variant in aldosterone synthase increasing CYP11B2 transcription, as...
|
Heart & Inflammation
|
|
Moderate
|
|
rs1801252
|
ADRB1
Ser49Gly
|
Beta-1 adrenergic receptor variant at position 49 affecting receptor downregu...
|
Fitness & Body
|
|
Strong
|
|
rs5068
|
NPPA
|
3'UTR variant that disrupts miR-425 binding, increasing atrial natriuretic pe...
|
Heart & Inflammation
|
|
Strong
|
|
rs1800764
|
ACE
Promoter T>C
|
Upstream promoter-region ACE variant on a separate LD block from the I/D poly...
|
Fitness & Body
|
|
Moderate
|
|
rs12917707
|
UMOD
|
Uromodulin promoter variant — strongest GWAS signal for chronic kidney diseas...
|
Vitamins & Micronutrients
|
|
Established
|
|
rs2270915
|
NPR3
N521D
|
Missense variant in NPR3 clearance receptor disrupting Gi protein coupling, i...
|
Heart & Inflammation
|
|
Moderate
|
|
rs4293393
|
UMOD
|
UMOD promoter variant affecting uromodulin expression, linked to CKD, salt-se...
|
Vitamins & Micronutrients
|
|
Established
|
|
rs891512
|
NOS3
|
Intronic NOS3 variant that alters splicing factor binding and is associated w...
|
Vitamins & Micronutrients
|
|
Moderate
|
|
rs1808593
|
NOS3
|
Intronic NOS3 variant associated with ankle-brachial index and peripheral art...
|
Vitamins & Micronutrients
|
|
Moderate
|