Tag

Asthma

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs1042713	ADRB2 Arg16Gly	Beta-2 adrenergic receptor variant affecting receptor downregulation, exercis...	Fitness & Body	Fitness Cardiovascular Beta-Agonist	Strong
rs61816761	FLG R501X	Nonsense variant eliminating filaggrin protein, the major genetic risk factor...	Immune & Gut	Skin Health Immune & Gut Inflammation	Established
rs1837253	TSLP Upstream Variant	Upstream regulatory variant in TSLP reducing cytokine expression; the protect...	Immune & Gut	Immune & Gut Asthma Inflammation	Strong
rs2569190	CD14 -159C>T	Promoter variant affecting CD14 expression and LPS receptor signaling — deter...	Immune & Gut	Immune & Gut Innate Immunity Inflammation	Strong
rs1801275	IL4R Q576R	Gain-of-function missense variant in the IL-4 receptor alpha chain that ampli...	Immune & Gut	Immune & Gut Immune System Asthma	Strong
rs558269137	FLG 2282del4	Frameshift deletion eliminating filaggrin protein, the second most common Eur...	Immune & Gut	Skin Health Immune & Gut Inflammation	Established
rs12730935	FLG 3702delG	Frameshift deletion in the third filaggrin repeat domain — the third most com...	Immune & Gut	Skin Health Immune & Gut Inflammation	Established
rs372628716	FLG S3247X	Nonsense variant eliminating filaggrin protein — a minor European FLG null al...	Immune & Gut	Skin Health Immune & Gut Inflammation	Strong
rs4696480	TLR2 T-16934A	Promoter variant in Toll-Like Receptor 2 that increases TLR2 expression, asso...	Immune & Gut	Innate Immunity Skin Health Inflammation	Moderate