Tag

B-Cell Signaling

6 genetic variants with this tag.

RSID	Gene	Description	Category
rs4810485	CD40	Intronic variant in CD40 regulating B-cell surface expression; the G allele d...	Immune & Gut	Immune & Autoimmune Rheumatoid Arthritis Inflammation	Strong
rs33980500	TRAF3IP2 D10N	Missense variant in Act1 that abolishes IL-17 signaling by disrupting TRAF6 b...	Immune & Gut	Immune System Autoimmune Inflammation	Strong
rs10516487	BANK1 R61H	BANK1 scaffold protein missense variant that shifts B-cell receptor signaling...	Immune & Gut	Autoimmune Lupus Immune System	Strong
rs13277113	BLK	Regulatory variant upstream of BLK that reduces B-lymphoid tyrosine kinase ex...	Immune & Gut	Autoimmune Lupus Immune System	Strong
rs3733197	BANK1 A383T	BANK1 ankyrin-domain missense variant that amplifies B-cell receptor signalin...	Immune & Gut	Autoimmune Lupus Immune System	Strong
rs1883832	CD40 Kozak -1C>T	Kozak sequence variant at position −1 of the CD40 start codon — the C allele ...	Immune & Gut	Immune & Autoimmune B-Cell Signaling Thyroid	Strong