Tag

Arthritis

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs2004640	IRF5 G198T	Intronic variant creating alternative splice site that increases type I inter...	Immune & Gut	Immune & Autoimmune Inflammation Interferon	Strong
rs33980500	TRAF3IP2 D10N	Missense variant in Act1 that abolishes IL-17 signaling by disrupting TRAF6 b...	Immune & Gut	Immune System Autoimmune Inflammation	Strong
rs2201841	IL23R	Intronic variant in the IL-23 receptor gene associated with increased risk of...	Immune & Gut	Immune & Gut Autoimmune Inflammation	Strong
rs26653	ERAP1	Missense variant (Arg127Pro) in ERAP1 that subtly alters ER peptide trimming ...	Immune & Gut	Immune System Autoimmune MHC Antigen Presentation	Strong
rs30187	ERAP1 K528R	Missense variant reducing ERAP1 aminopeptidase activity, increasing ankylosin...	Immune & Gut	Immune System Autoimmune Inflammation	Strong
rs13210247	TRAF3IP2	Intronic variant in the TRAF3IP2 locus that lies within the antisense lncRNA ...	Immune & Gut	Immune & Gut Autoimmune Inflammation	Strong
rs13190932	TRAF3IP2 R74W	Missense variant in the IL-17 adaptor Act1 (Arg74Trp) that is the primary GWA...	Immune & Gut	Immune & Gut Autoimmune Inflammation	Strong
rs7517847	IL23R	Intronic IL23R variant in which the T allele increases susceptibility to Croh...	Immune & Gut	Immune & Gut Autoimmune IBD	Strong
rs1004819	IL23R	Intronic IL-23 receptor variant that increases susceptibility to ankylosing s...	Immune & Gut	Inflammation Autoimmune IBD	Strong