Tag

Smoking Interaction

6 genetic variants with this tag.

RSID	Gene	Description	Category
rs1799793	ERCC2 D312N	Missense variant in the XPD helicase that reduces nucleotide excision repair ...	Cancer Risk	Cancer Risk DNA Repair Cancer Screening	Strong
rs1061170	CFH Y402H	Strongly increases risk of age-related macular degeneration through impaired ...	Skin & Eyes	Eye Health Inflammation Cardiovascular	Established
rs25487	XRCC1 R399Q	Base excision repair scaffold protein that coordinates repair of oxidative DN...	Cancer Risk	Cancer Risk DNA Repair Base Excision Repair	Strong
rs1799782	XRCC1 R194W	Missense variant in the linker region of XRCC1 that disrupts interaction with...	Cancer Risk	Cancer Risk DNA Repair Base Excision Repair	Strong
rs2470890	CYP1A2 Asn516= (exon 7)	Synonymous variant in CYP1A2 exon 7 in linkage disequilibrium with the *1F hi...	Cancer Risk	Cancer Risk Carcinogen Metabolism Detoxification	Strong
rs2228000	XPC Ala499Val	Missense variant in the DNA damage recognition gene XPC that moderately reduc...	Cancer Risk	Cancer Risk DNA Repair Bladder Cancer	Moderate